![]() Matsa, E., Dixon, J.E., Medway, C., Georgiou, O., Patel, M.J., Morgan, K., Kemp, P.J., Staniforth, A., Mellor & Denning. (2013) Rnf165/Ark2C Enhances BMP-Smad Signaling to Mediate Motor Axon Extension. Combined hydrogels that switch human pluripotent stem cells from self-renewal to differentiation. Improve architectural control in engineered tissues from human stem cellsÄixon, J.E., Shah, D.A., Rogers, C., Hall, S., Weston, N., McNally, D., Denning, C.Develop in vivo delivery and triggered delivery systems for therapeutics.Investigate potential applications of this technology for differentiating human stem cells.Devise cell-type specific delivery systems for therapeutic molecules.Design and manufacture of intracellular delivery systems to control cell behaviour. ![]() My interests include regenerative medicine applications for a peptide delivery system I developed within the Tissue engineering group, University of Nottingham and fundamental stem cell biology research. I am named inventor on several patents and am presently leading research to develop intracellular delivery technologies for the UKRMP Acellular hub. In 2008 I took up a Postdoctoral research post at the University of Nottingham Spin-out company EvoCell and in 2009 transferred to the Wolfson STEM centre at the University of Nottingham within the Tissue Engineering group of Kevin Shakesheff. I gained my Honours degree from Edinburgh (BSc Genetics) and my PhD from Imperial College, London under the supervision of Vasso Episkopou at the MRC Clinical Sciences Centre. I am a Stem cell and molecular biologist.
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